MAPK7
Reactivité: Humain, Souris, Rat
WB, IF (cc), FACS, IHC (p)
Hôte: Lapin
Monoclonal
8D8
unconjugated
Indications d'application
ELISA: 1/10000
Restrictions
For Research Use only
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Antigène
MAPK7
(Mitogen-Activated Protein Kinase 7 (MAPK7))
Autre désignation
MAPK7
Sujet
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.